The hypothalamic-pituitary-adrenal axis in anxiety and panic.

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The hypothalamic-pituitary-adrenal axis in anxiety and panic

This review article focuses on the differential activation of the hypothalamic-pituitary-adrenal (HPA) axis in generalized anxiety and panic. The results of experimental studies that assayed adrenocorticotropic hormone, cortisol and prolactin show that real-life panic attacks as well as those induced by selective panicogenic agents, such as lactate and carbon dioxide, do not activate the HPA ax...

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[Anxiety, panic and the hypothalamic-pituitary-adrenal axis].

OBJECTIVE This article focuses on the differential activation of the hypothalamic-pituitary-adrenal axis in generalized anxiety disorder and panic disorder. METHOD The results of recently reported reviews of the literature are summarized and discussed. RESULTS The results of experimental studies that assayed adrenocorticotropic hormone, cortisol and prolactin show that real-life panic attac...

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Does the panic attack activate the hypothalamic-pituitary-adrenal axis?

A bibliographic search has been performed in MEDLINE using cortisol and panic as key-words, occurring in the title and/or in the abstract. Human studies were selected, with no time limit. The following publications were excluded: review articles, case reports, panic attacks in disorders other than panic disorder, and studies on changes that occurred in-between panic attacks. The results showed ...

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Neuroendocrine Regulation of Anxiety: Beyond the Hypothalamic-Pituitary-Adrenal Axis.

The central nervous system regulates and responds to endocrine signals, and this reciprocal relationship determines emotional processing and behavioural anxiety. Although the hypothalamic-pituitary-adrenal (HPA) axis remains the best-characterised system for this relationship, other steroid and peptide hormones are increasingly recognised for their effects on anxiety-like behaviour and reward. ...

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Anxiety disorders and hypothalamic - pituitary - adrenal axis activity Chapter 4

Background Anxiety disorders have been suggested to be linked to hypothalamic-pituitary-adrenal (HPA) axis activity, although results are scarce and inconsistent. No earlier studies have examined consistency of HPA axis findings across several anxiety subtypes and whether associations are state or trait dependent. Our objective was to examine the association between several subtypes of anxiety ...

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ژورنال

عنوان ژورنال: Psychology & Neuroscience

سال: 2010

ISSN: 1983-3288,1984-3054

DOI: 10.3922/j.psns.2010.1.002